Lee most recently served as the chief financial officer (CFO) and chief operating officer (COO) of investing application Acorns. Before that, she spent eight years at PayPal in top executive roles.
Her appointment comes at a time when investors have been dumping digital assets on fears that aggressive interest rate hikes from global central banks would spark an economic slowdown.
The crypto industry has also been in the crosshairs of regulators who worry that the meltdown in the volatile market could hit the broader financial sector. That has prompted a push for more rules on the largely unregulated industry.
“Her experience at Paypal … will be invaluable as we chart our path to an IPO in the coming years,” said Chief Executive Brian Shroder in a statement.
Lee replaces interim CFO Eric Segal, who had held the role since October and has now left the company, the Wall Street Journal reported, citing a company spokesman.
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Launched in 2019, Binance.US had fetched a pre-money valuation of $4.5 billion in April when it raised $200 million in a funding round.
Last year, the company’s former chief executive Brian Brooks resigned just three months after taking up the role.